Lead is a neurotoxin. This has been known for a long time, & in fact government regulation
drastically reduced environmental lead a generation ago. But regulating automobile fuel &
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paint didn’t entirely eliminate lead from the environment. It’s found in trace amounts in
Every American today is exposed to low levels of the metal, & indeed all babies .
have measureable levels of lead in their bodies. According to psychological scientist Joel
an ideal candidate for the disorder’s trigger.Nigg of the Oregon Health & Science
University, this universal low-level exposure makes lead This was a theory until recently,
but three recent studies now provide strong evidence. The first study compared babies
formally diagnosed with ADHD to controls, & found that the babies with the disorder had
slightly higher levels of lead in their blood. This study showed a link only between blood
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symptoms, not inattention. But a second study showed a robust link
between blood lead & both parent & teacher ratings of ADHD symptoms, including both
hyperactivity & attention problems. In during pregnancy.
both studies, the connection was independent of IQ, relatives income, race, or maternal
smoking sites in the brain’s striatum & frontal cortex, where it acts on the genes in these
Nigg offers a causal model for the disabling symptoms associated with ADHD: Lead attaches to
regions—causing them to turn on or remain inactive. Gene activity shapes the development &
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. By disrupting brain activity, the toxin in turn alters